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1. The effects of drug phosphatidycholine ratio, pluronic F 68 concentration and glycerol tristearate concentration on the mean particle size, entrapment ratio and drug loading were investigated.
结果 平均粒径、包封率、载药量和综合指标拟合所得多元二次方程的复相关系数分别为 0 93 93 ，0 773 9，0 980 1和 0 83 69。优化条件制备的药质体的平均粒径、包封率和载药量分别为 76nm ，97 4 9%和